MODY in Ukraine: genes, clinical phenotypes and treatment
نویسندگان
چکیده
منابع مشابه
Renal MODY-fier genes.
IT IS SUPPOSED that every gene in the body has a constellation of controlling elements serving as binding sites for transcription factors working coordinately in a tissue-specific, temporal, and/or developmental fashion. These DNA elements are bound by a community of protein factors organized around transcription start sites to regulate the relative activities and levels of expression of genes ...
متن کاملNeonatal diabetes in Ukraine: incidence, genetics, clinical phenotype and treatment.
BACKGROUND Neonatal diabetes has not been previously studied in Ukraine. We investigated the genetic etiology in patients with onset of diabetes during the first 9 months of life. METHODS We established a Pediatric Diabetes Register to identify patients diagnosed with diabetes before 9 months of age. Genetic testing was undertaken for 42 patients with permanent or transient diabetes diagnosed ...
متن کاملMody
EARLY HISTORY—In the academic year 1949–1950, one of us (S.S.F.), while a first-year Fellow in Endocrinology and Metabolism at the University of Michigan (Jerome W. Conn, Division Chief), initiated a prospective, long-term study on the diagnosis, natural history, and clinical genetics of diabetes. Starting with known diabetic patients from the Diabetes Clinic, I recruited their apparently healt...
متن کاملClinical features and treatment of maturity onset diabetes of the young (MODY)
Maturity onset diabetes of the young (MODY) is a heterogeneous group of disorders that result in β-cell dysfunction. It is rare, accounting for just 1%-2% of all diabetes. It is often misdiagnosed as type 1 or type 2 diabetes, as it is often difficult to distinguish MODY from these two forms. However, diagnosis allows appropriate individualized care, depending on the genetic etiology, and allow...
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ژورنال
عنوان ژورنال: Clinical endocrinology and endocrine surgery
سال: 2017
ISSN: 2519-2582,1818-1384
DOI: 10.24026/1818-1384.3(59).2017.110893